Symptoms of Postpartum Depression and Perinatal Mental Health Disorders

Perinatal mental health conditions—including postpartum depression—can present in a variety of emotional, behavioral, and physical symptoms. These symptoms may vary in severity and can affect both your well-being and your ability to care for your baby. It’s important to remember that experiencing any of the following signs is not a sign of weakness or failure as a parent, but rather an indicator that support and professional help may be needed.

Common Symptoms May Include:

  • Persistent sadness, emptiness, or hopelessness

  • Feeling emotionally or physically overwhelmed

  • Crying frequently without a clear reason

  • Irritability, anger, or sudden mood swings

  • Difficulty sleeping (even when the baby is asleep) or excessive sleeping

  • Loss of interest in activities once enjoyed

  • Problems with concentration or focus

  • Ongoing physical pain or discomfort without a medical cause

  • Extreme fatigue or low energy

  • Changes in eating habits (overeating or lack of appetite)

  • Social withdrawal or avoiding family and friends

  • Trouble forming a bond with your baby

  • Doubting your ability to care for your child

  • Fear of being left alone with your baby

  • Thoughts of self-harm or harming the baby

  • Severe anxiety, restlessness, or nervousness

  • Constant sense of dread or fear that something bad will happen

  • Flashbacks or nightmares related to birth trauma

  • Avoidance of people or places that trigger traumatic memories

  • Confusion or difficulty organizing thoughts

  • Hallucinations or hearing/seeing things that aren’t there

  • Delusional thinking or irrational beliefs

  • Disturbing or intrusive thoughts

  • Disorganized speech or erratic behavior

What Is Postpartum Depression?

While many new mothers experience short-term emotional shifts known as the “baby blues,” postpartum depression (PPD) goes far beyond temporary mood swings. When feelings of sadness, hopelessness, or extreme fatigue interfere with everyday life and parenting responsibilities, it may be a sign of postpartum depression. This condition can also develop during pregnancy—referred to as antepartum depression—and is part of a broader category of perinatal mental health disorders (meaning conditions that occur during or after pregnancy).

Perinatal mental health conditions include:

  • Antepartum and Postpartum Depression

  • Perinatal Anxiety Disorders

  • Perinatal Obsessive-Compulsive Disorder (OCD)

  • Birth-related Trauma and PTSD

  • Perinatal Bipolar Disorder

  • Perinatal Psychosis or Schizophrenia



How Common Is Postpartum Depression?

Postpartum depression and related perinatal mental health issues are more common than many realize. Approximately 25% of women experience depression or another mood disorder within the first year after giving birth. In fact, this period is the most vulnerable time in a woman’s life to develop depression.

Experts believe these conditions are significantly underdiagnosed and undertreated, with less than 40% of mothers receiving the help they need.

Men can be affected too. Studies show that 10% of new fathers develop symptoms of postpartum depression, and that number can climb to 26% within the first 3 to 6 months postpartum—especially if their partner is also struggling with perinatal mental health challenges.

What Causes Postpartum Depression?

Postpartum and perinatal mood disorders result from a combination of factors. These include:

  • Hormonal fluctuations during and after pregnancy

  • Emotional stress related to new responsibilities

  • Financial strain and lack of social or familial support

  • History of depression, anxiety, or other mental health issues

  • Family history of psychiatric conditions

What Are the Consequences of Postpartum Depression?

When left untreated, postpartum depression can negatively affect both mother and child. Impacts on the baby may include:

  • Developmental delays

  • Impaired emotional and cognitive development

  • Poor stress management later in life

  • Increased risk of anxiety and depression during childhood and adolescence

Impact on Mother–Infant Bonding

Perinatal mental health disorders can interfere with a mother’s ability to bond and engage with her child, leading to:

  • Difficulty with breastfeeding

  • Emotional detachment from the baby

  • Skipping pediatric wellness visits

  • Inadequate use of car seats or other infant safety measures

  • Failure to baby-proof the home (e.g., outlet covers, safety latches)

  • Limited engagement such as lack of eye contact, smiling, reading, singing, or touching

Getting help early is essential—for both mother and baby. If you or someone you love is experiencing symptoms of postpartum depression or any perinatal mental health issue, seek support from a qualified professional.

Symptoms of Postpartum Depression and Perinatal Mental Health Disorders

Perinatal mental health conditions—including postpartum depression—can present in a variety of emotional, behavioral, and physical symptoms. These symptoms may vary in severity and can affect both your well-being and your ability to care for your baby. It’s important to remember that experiencing any of the following signs is not a sign of weakness or failure as a parent, but rather an indicator that support and professional help may be needed.

Common Symptoms May Include:

  • Persistent sadness, emptiness, or hopelessness

  • Feeling emotionally or physically overwhelmed

  • Crying frequently without a clear reason

  • Irritability, anger, or sudden mood swings

  • Difficulty sleeping (even when the baby is asleep) or excessive sleeping

  • Loss of interest in activities once enjoyed

  • Problems with concentration or focus

  • Ongoing physical pain or discomfort without a medical cause

  • Extreme fatigue or low energy

  • Changes in eating habits (overeating or lack of appetite)

  • Social withdrawal or avoiding family and friends

  • Trouble forming a bond with your baby

  • Doubting your ability to care for your child

  • Fear of being left alone with your baby

  • Thoughts of self-harm or harming the baby

  • Severe anxiety, restlessness, or nervousness

  • Constant sense of dread or fear that something bad will happen

  • Flashbacks or nightmares related to birth trauma

  • Avoidance of people or places that trigger traumatic memories

  • Confusion or difficulty organizing thoughts

  • Hallucinations or hearing/seeing things that aren’t there

  • Delusional thinking or irrational beliefs

  • Disturbing or intrusive thoughts

  • Disorganized speech or erratic behavior

Postpartum Depression, Perinatal Mental Health Disorders, and Brain Function

Perinatal mental health conditions are complex and stem from more than just emotional strain. Brain imaging studies, such as SPECT scans, reveal distinct patterns of brain activity linked to various perinatal disorders. These findings provide deeper insight into the biological roots of these conditions and help guide more accurate diagnosis and effective treatment.

How the Brain Is Affected by Different Perinatal Conditions:

  • Depression: Postpartum and pregnancy-related depression is often tied to increased activity in the brain’s limbic system, which regulates mood and emotions. This pattern has also been observed in animal studies.

  • Anxiety: Perinatal anxiety is typically linked to overactivity in regions such as the basal ganglia, amygdala, hippocampus, insula, and portions of the prefrontal cortex, leading to heightened stress responses and excessive worry.

  • Obsessive-Compulsive Disorder (OCD): When OCD symptoms emerge during or after pregnancy, they are commonly associated with heightened activity in the anterior cingulate gyrus—a part of the brain involved in shifting attention. Overactivity here can lead to obsessive thoughts and compulsive behaviors.

  • Post-Traumatic Stress Disorder (PTSD): Traumatic birth experiences—whether physically or emotionally distressing—can reset the brain to a hyper-alert state, leading to PTSD. Approximately 9% of postpartum women are affected. Increased activity is seen in the limbic system, basal ganglia, and anterior cingulate gyrus in these cases.

  • Bipolar Disorder: Characterized by alternating episodes of depression and mania, perinatal bipolar disorder may be misdiagnosed as depression or ADHD. Brain imaging can help differentiate bipolar disorder by identifying unique activity patterns.

  • Psychosis or Schizophrenia: Perinatal psychosis is a severe condition often related to neurotransmitter imbalances. It typically results in decreased activity in the prefrontal cortex, impacting judgment, cognition, and emotional regulation.